The "three" alluded to in the title are played by Jim Brown, Fred Williamson and Jim Kelly. Letting their fists do all the talking, the hard-nosed trio takes on a neofascist organization. It is the avowed purpose of this all-white hate group to "cleanse" Los Angeles, Detroit and Washington DC of all blacks. To do this, they plan to poison the drinking water with a secret formula that affects only African Americans.